
Researchers at McGill University have discovered a molecular basis for the cancer preventive effects of vitamin D, whereby its active form essentially shuts down cancer cells.
People with higher blood levels of vitamin D live significantly longer than people who have low blood levels of the vitamin.
The team, led by McGill professors John White and David Goltzman, of the Faculty of Medicine’s Department of Physiology, discovered that the active form of vitamin D acts by several mechanisms to inhibit both the production and function of the protein cMYC.
cMYC drives cell division and is active at elevated levels in more than half of all cancers. Their results are published in the latest edition of Proceedings of the National Academy of Sciences.
For the past several years, there has been considerable interest in the role vitamin D plays in improving health and preventing disease. Previous finding show that low levels of vitamin D have been directly associated with various forms of cancer and cardiovascular disease. Stephen B. Kritchevsky, PhD, Professor of Internal Medicine and Transitional Science at the Wake Forest School of Medicine found a signficant correlation.
“We observed vitamin D insufficiency (defined as blood levels <20 ng/ml), in one third of our study participants. This was associated with nearly a 50 percent increase in the mortality rate in older adults,” said Kritchevsky. “Our findings suggest that low levels of vitamin D may be a substantial public health concern for our nation’s older adults.”
The post Canadian Researchers Discover New Evidence That Vitamin D Shuts Down Cancer Cells appeared first on Daily Health Post.
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